Rebecca Giguere; Iván C. Balán; Bryan A. Kutner; Seul Ki Choi; Ryan Tingler; Sherri Johnson; Nicole Macagna; Jessica Webster; Al Liu; Suwat Chariyalertsak; Craig Hoesley; Pedro Gonzales; Ken Ho; Noel Kayange; Thesla Palanee-Phillips; Elizabeth Brown; Jillian Zemanek; Cindy E. Jacobson; Gustavo F. Doncel; Jeanna Piper; José A. Bauermeister;
In: AIDS Behav, vol. 28, no. 8, pp. 2577–2589, 2024, ISSN: 1573-3254.
@article{Giguere2024,
title = {History of Rectal Product Use and Country of Residence Influence Preference for Rectal Microbicide Dosage Forms Among Young Sexual and Gender Minorities: A Multi-country Trial Comparing Placebo Douche, Suppository, and Insert Products},
author = {Rebecca Giguere and Iván C. Balán and Bryan A. Kutner and Seul Ki Choi and Ryan Tingler and Sherri Johnson and Nicole Macagna and Jessica Webster and Al Liu and Suwat Chariyalertsak and Craig Hoesley and Pedro Gonzales and Ken Ho and Noel Kayange and Thesla Palanee-Phillips and Elizabeth Brown and Jillian Zemanek and Cindy E. Jacobson and Gustavo F. Doncel and Jeanna Piper and José A. Bauermeister and },
doi = {10.1007/s10461-024-04360-9},
issn = {1573-3254},
year = {2024},
date = {2024-08-00},
journal = {AIDS Behav},
volume = {28},
number = {8},
pages = {2577--2589},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Sarah M. Wood; José Bauermeister; Alexander G. Fiks; Alexis W. Phillips; Haley M. Richardson; Stephanie M. Garcia; Pegah Maleki; Rinad S. Beidas; Jami F. Young; Robert Gross; Nadia Dowshen
Adolescent Preferences for a Pediatric Primary Care-based Sexually Transmitted Infection and HIV Prevention Intervention Journal Article
In: Journal of Adolescent Health, vol. 74, no. 6, pp. 1231–1238, 2024, ISSN: 1054-139X.
@article{Wood2024,
title = {Adolescent Preferences for a Pediatric Primary Care-based Sexually Transmitted Infection and HIV Prevention Intervention},
author = {Sarah M. Wood and José Bauermeister and Alexander G. Fiks and Alexis W. Phillips and Haley M. Richardson and Stephanie M. Garcia and Pegah Maleki and Rinad S. Beidas and Jami F. Young and Robert Gross and Nadia Dowshen},
doi = {10.1016/j.jadohealth.2024.01.033},
issn = {1054-139X},
year = {2024},
date = {2024-06-00},
journal = {Journal of Adolescent Health},
volume = {74},
number = {6},
pages = {1231--1238},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
José A. Bauermeister; Jessica Halem
Breaking Down Silos to Accelerate Innovation in LGBTQ+ Health Journal Article
In: Am J Health Promot, vol. 38, no. 3, pp. 431–435, 2024, ISSN: 2168-6602.
@article{Bauermeister2024,
title = {Breaking Down Silos to Accelerate Innovation in LGBTQ+ Health},
author = {José A. Bauermeister and Jessica Halem},
doi = {10.1177/08901171241232057b},
issn = {2168-6602},
year = {2024},
date = {2024-03-00},
urldate = {2024-03-00},
journal = {Am J Health Promot},
volume = {38},
number = {3},
pages = {431--435},
publisher = {SAGE Publications},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Beans Velocci
The history of sex research: Is “sex” a useful category? Journal Article
In: Cell, vol. 187, no. 6, pp. 1343–1346, 2024, ISSN: 0092-8674.
@article{Velocci2024,
title = {The history of sex research: Is “sex” a useful category?},
author = {Beans Velocci},
doi = {10.1016/j.cell.2024.02.001},
issn = {0092-8674},
year = {2024},
date = {2024-03-00},
journal = {Cell},
volume = {187},
number = {6},
pages = {1343--1346},
publisher = {Elsevier BV},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
José Bauermeister; Willey Lin; Ryan Tingler; Albert Liu; Suwat Chariyalertsak; Craig Hoesley; Pedro Gonzales; Ken Ho; Noel Kayange; Thesla Palanee Phillips; Sherri Johnson; Elizabeth Brown; Jillian Zemanek; Cindy E. Jacobson; Gustavo F. Doncel; Jeanna Piper;
A conjoint experiment of three placebo rectal products used with receptive anal sex: results from MTN‐035 Journal Article
In: J Int AIDS Soc., vol. 27, no. 3, 2024, ISSN: 1758-2652.
@article{Bauermeister2024d,
title = {A conjoint experiment of three placebo rectal products used with receptive anal sex: results from MTN‐035},
author = {José Bauermeister and Willey Lin and Ryan Tingler and Albert Liu and Suwat Chariyalertsak and Craig Hoesley and Pedro Gonzales and Ken Ho and Noel Kayange and Thesla Palanee Phillips and Sherri Johnson and Elizabeth Brown and Jillian Zemanek and Cindy E. Jacobson and Gustavo F. Doncel and Jeanna Piper and },
doi = {10.1002/jia2.26219},
issn = {1758-2652},
year = {2024},
date = {2024-03-00},
journal = {J Int AIDS Soc.},
volume = {27},
number = {3},
publisher = {Wiley},
abstract = {Abstract Introduction End‐user perspectives are vital to the design of new biomedical HIV prevention products. Conjoint analysis can support the integration of end‐user perspectives by examining their preferences of potential pre‐exposure prophylaxis (PrEP) products. The Microbicides Trial Network (MTN) 035 protocol examined three placebo rectal dosage forms (insert, enema and suppository) that could deliver PrEP prior to receptive anal sex (RAS). Methods Between April 2019 and July 2020, we enrolled 217 HIV‐negative, cisgender men who have sex with men (MSM; n = 172; 79.3%) and transgender people (n = 47; 20.7%) ages 18–35 into a randomized cross‐over trial across Malawi, Peru, South Africa, Thailand and the United States. Participants used each product prior to RAS over 4‐week periods. Participants completed a conjoint experiment where they selected between random profiles using seven features (dosage form, timing of use before sex, side effects, duration of protection, effectiveness, frequency of use and need for a prescription). Results Effectiveness was the strongest determinant of choice (30.4%), followed by modality (18.0%), potential side effects (17.2%), frequency of use (10.8%), duration of protection (10.4%), timing of use before sex (7.4%) and need for a prescription (5.9%). Relative utility scores indicated that the most desirable combination of attributes was a product with 95% efficacy, used 30 minutes before sex, offering a 3‐ to 5‐day protection window, used weekly, having no side effects, in the form of an enema and available over‐the‐counter. Conclusions Choice in next‐generation PrEP products is highly desired by MSM and transgender people, as no one‐size‐fits‐all approach satisfies all the preferences. MTN‐035 participants weighed product features differently, recognizing the need for diverse, behaviourally congruent biomedical options that fit the needs of intended end‐users. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dovie L. Watson; Louis Listerud; Ryan A. Drab; Willey Y. Lin; Florence Marie Momplaisir; José A. Bauermeister
In: J Int AIDS Soc., vol. 27, no. 2, 2024, ISSN: 1758-2652.
@article{Watson2024,
title = {HIV pre‐exposure prophylaxis programme preferences among sexually active HIV‐negative transgender and gender diverse adults in the United States: a conjoint analysis},
author = {Dovie L. Watson and Louis Listerud and Ryan A. Drab and Willey Y. Lin and Florence Marie Momplaisir and José A. Bauermeister},
doi = {10.1002/jia2.26211},
issn = {1758-2652},
year = {2024},
date = {2024-02-00},
journal = {J Int AIDS Soc.},
volume = {27},
number = {2},
publisher = {Wiley},
abstract = {Abstract Introduction Current implementation efforts have failed to achieve equitable HIV pre‐exposure prophylaxis (PrEP) provision for transgender and gender‐diverse (trans) populations. We conducted a choice‐based conjoint analysis to measure preferences for key attributes of hypothetical PrEP delivery programmes among a diverse online sample predominantly comprised of transmasculine and nonbinary individuals in the United States. Methods Between April 2022 and June 2022, a national online survey with an embedded conjoint analysis experiment was conducted among 304 trans individuals aged ≥18 years in the United States to assess five PrEP programme attributes: out‐of‐pocket cost; dispensing venue; frequency of visits for PrEP‐related care; travel time to PrEP provider; and ability to bundle PrEP‐related care with gender‐affirming hormone therapy services. Participants responded to five questions, each of which presented two PrEP programme scenarios and one opt‐out option per question and selected their preferred programme in each question. We used hierarchical Bayes estimation and multinomial logistic regression to measure part‐worth utility scores for the total sample and by respondents’ PrEP status. Results The median age was 24 years (range 18–56); 75% were assigned female sex at birth; 54% identified as transmasculine; 32% as nonbinary; 14% as transfeminine. Out‐of‐pocket cost had the highest attribute importance score (44.3%), followed by the ability to bundle with gender‐affirming hormone therapy services (18.7%). Minimal cost‐sharing ($0 out‐of‐pocket cost) most positively influenced the attribute importance of cost (average conjoint part‐worth utility coefficient of 2.5 [95% CI 2.4−2.6]). PrEP‐experienced respondents preferred PrEP delivery in primary care settings (relative utility score 4.7); however, PrEP‐naïve respondents preferred pharmacies (relative utility score 5.1). Conclusions Participants preferred programmes that offered PrEP services without cost‐sharing and bundled with gender‐affirming hormone therapy services. Bolstering federal regulations to cover PrEP services and prioritizing programmes to expand low‐barrier PrEP provision are critical to achieving equitable PrEP provision. Community‐engaged implementation research conducted by and in close collaboration with trans community stakeholders and researchers are needed to streamline the design of patient‐centred PrEP programmes and develop implementation strategies that are salient to the diverse sexual health needs of trans patients. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Hyunmin Yu; Dalmacio Dennis Flores; Stephen Bonett; José Arturo Bauermeister
LGBTQ + cultural competency training for health professionals: a systematic review Journal Article
In: BMC Med Educ, vol. 23, no. 1, 2023, ISSN: 1472-6920.
@article{Yu2023b,
title = {LGBTQ + cultural competency training for health professionals: a systematic review},
author = {Hyunmin Yu and Dalmacio Dennis Flores and Stephen Bonett and José Arturo Bauermeister},
doi = {10.1186/s12909-023-04373-3},
issn = {1472-6920},
year = {2023},
date = {2023-12-00},
journal = {BMC Med Educ},
volume = {23},
number = {1},
publisher = {Springer Science and Business Media LLC},
abstract = {Abstract
Background
Health disparities experienced by LGBTQ + individuals have been partially attributed to health professionals’ lack of cultural competence to work with them. Cultural competence, the intricate integration of knowledge, skills, attitudes, and behaviors that improve cross-cultural communication and interpersonal relationships, has been used as a training framework to enhance interactions between LGBTQ + patients and health professionals. Despite multiple published LGBTQ + cultural competency trainings, there has been no quantitative appraisal and synthesis of them. This systematic review assessed articles evaluating the design and effectiveness of these trainings and examined the magnitude of their effect on cultural competence outcomes.
Methods
Included studies quantitatively examined the effectiveness of LGBTQ + cultural competency trainings for health professionals across all disciplines in various healthcare settings. 2,069 citations were retrieved from five electronic databases with 44 articles meeting inclusion criteria. The risk of bias in the included studies was assessed by two authors utilizing the Joanna Briggs Institute critical appraisal checklists. Data extracted included study design, country/region, sample characteristic, training setting, theoretical framework, training topic, modality, duration, trainer, training target, measurement instrument, effect size and key findings. This review followed the PRISMA statement and checklist to ensure proper reporting.
Results
75% of the studies were published between 2017 and 2023. Four study designs were used: randomized controlled trial (n = 1), quasi-experimental pretest–posttest without control (n = 39), posttest only with control (n = 1) and posttest only without control (n = 3). Training modalities were multiple modalities with (n = 9) and without simulation (n = 25); single modality with simulation (n = 1); and with didactic lectures (n = 9). Trainings averaged 3.2 h. Ten studies employed LGBTQ + trainers. The training sessions resulted in statistically significant improvements in the following cultural competence constructs: (1) knowledge of LGBTQ + culture and health (n = 28, effect size range = 0.28 – 1.49), (2) skills to work with LGBTQ + clients (n = 8, effect size range = 0.12 – 1.12), (3) attitudes toward LGBTQ + individuals (n = 14, effect size range = 0.19 – 1.03), and (4) behaviors toward LGBTQ + affirming practices (n = 7, effect size range = 0.51 – 1.11).
Conclusions
The findings of this review highlight the potential of LGBTQ + cultural competency training to enhance cultural competence constructs, including (1) knowledge of LGBTQ + culture and health, (2) skills to work with LGBTQ + clients, (3) attitudes toward LGBTQ + individuals, and (4) behaviors toward LGBTQ + affirming practices, through an interdisciplinary and multi-modal approach. Despite the promising results of LGBTQ + cultural competency training in improving health professionals’ cultural competence, there are limitations in study designs, sample sizes, theoretical framing, and the absence of longitudinal assessments and patient-reported outcomes, which call for more rigorous research. Moreover, the increasing number of state and federal policies that restrict LGBTQ + health services highlight the urgency of equipping health professionals with culturally responsive training. Organizations and health systems must prioritize organizational-level changes that support LGBTQ + inclusive practices to provide access to safe and affirming healthcare services for LGBTQ + individuals.
},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Seul Ki Choi; Kathryn E. Muessig; Lisa B. Hightow-Weidman; José A. Bauermeister
Paradata: Measuring Engagement in Digital HIV Interventions for Sexual and Gender Minorities Journal Article
In: Curr HIV/AIDS Rep, vol. 20, no. 6, pp. 487–501, 2023, ISSN: 1548-3576.
@article{Choi2023,
title = {Paradata: Measuring Engagement in Digital HIV Interventions for Sexual and Gender Minorities},
author = {Seul Ki Choi and Kathryn E. Muessig and Lisa B. Hightow-Weidman and José A. Bauermeister},
doi = {10.1007/s11904-023-00679-5},
issn = {1548-3576},
year = {2023},
date = {2023-12-00},
journal = {Curr HIV/AIDS Rep},
volume = {20},
number = {6},
pages = {487--501},
publisher = {Springer Science and Business Media LLC},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Victoria L. Phillips; Ashley Xue; Marné Castillo; Dalia Santiago; Taylor Wimbly; Lisa B. Hightow-Weidman; Rob Stephenson; José A. Bauermeister
In: Health Econ Rev, vol. 13, no. 1, 2023, ISSN: 2191-1991.
@article{Phillips2023,
title = {Cost of peer mystery shopping to increase cultural competency in community clinics offering HIV/STI testing to young men who have sex with men: results from the get connected trial},
author = {Victoria L. Phillips and Ashley Xue and Marné Castillo and Dalia Santiago and Taylor Wimbly and Lisa B. Hightow-Weidman and Rob Stephenson and José A. Bauermeister},
doi = {10.1186/s13561-023-00447-6},
issn = {2191-1991},
year = {2023},
date = {2023-12-00},
journal = {Health Econ Rev},
volume = {13},
number = {1},
publisher = {Springer Science and Business Media LLC},
abstract = {Abstract Introduction Cultural competency has been identified as a barrier to lesbian, gay, bisexual and transgender (LGBT) populations seeking care. Mystery shopping has been widely employed in the formal health care sector as a quality improvement (QI) tool to address specific client needs. The approach has had limited use in community-based organizations due in part to lack of knowledge and resource requirement concerns. Several mystery shopping initiatives are now being implemented which focus on the LGBT population with the goal of reducing barriers to accessing care. One subset targets men who have sex with men (MSM) to increase uptake of human immunodeficiency virus (HIV) testing. No study investigates the costs of these initiatives. Get Connected was a randomized control trial with the objective of increasing uptake of HIV-prevention services among young men who have sex with men (YMSM) through use of a resource-locator application (App). The initial phase of the trial employed peer-led mystery shopping to identify culturally competent HIV testing sites for inclusion in the App. The second phase of the trial randomized YMSM to test the efficacy of the App. Our objective was to determine the resource inputs and costs of peer-led mystery shopping to identify clinics for inclusion in the App as costs would be critical in informing possible adoption by organizations and sustainability of this model. Methods Through consultation with study staff, we created a resource inventory for undertaking the community-based, peer-led mystery shopping program. We used activity-based costing to price each of the inputs. We classified inputs as start-up and those for on-going implementation. We calculated costs for each category, total costs and cost per mystery shopper visit for the four-month trial and annually to reflect standard budgeting periods for data collected from September of 2019 through September of 2020. Results Recruitment and training of peer mystery shoppers were the most expensive tasks. Average start-up costs were $10,001 (SD $39.8). Four-month average implementation costs per visit were $228 (SD $1.97). Average annual implementation costs per visit were 33% lower at $151 (SD $5.60). Conclusions Peer-led, mystery shopping of HIV-testing sites is feasible, and is likely affordable for medium to large public health departments. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Jennifer T. Tran; Nele Loecher; Kristin A. Kosyluk; José A. Bauermeister
Anti‐LGBTQ+ sex education laws: The effects on students and implications for schools and school practitioners Journal Article
In: Psychology in the Schools, vol. 60, no. 12, pp. 5062–5075, 2023, ISSN: 1520-6807.
@article{Tran2023,
title = {Anti‐LGBTQ+ sex education laws: The effects on students and implications for schools and school practitioners},
author = {Jennifer T. Tran and Nele Loecher and Kristin A. Kosyluk and José A. Bauermeister},
doi = {10.1002/pits.23013},
issn = {1520-6807},
year = {2023},
date = {2023-12-00},
journal = {Psychology in the Schools},
volume = {60},
number = {12},
pages = {5062--5075},
publisher = {Wiley},
abstract = {Abstract Anti‐Lesbian, Gay, Bisexual, Trans, and/or Queer (LGBTQ+) education laws are defined as laws that prohibit or limit schools from discussing same‐sex relationships, broader sexuality, and gender issues in their sexual education curriculum. This study presents a historical context of anti‐LGBTQ+ sex education laws, examines the extant literature on the possible impact of these laws, and suggests recommendations for schools and school practitioners. Anti‐LGBTQ+ sex education laws may impact school climate and have been associated with poorer well‐being for LGBTQ+ students and cisgender heterosexual allies that encompass a range of sexual orientations and gender identities. With an Executive Order from the US president outlining the need to support LGBTQ+ youth in schools and the US Surgeon General's Advisory to highlight the urgent need to address the nation's youths' mental health, it is imperative to support LGBTQ+ students. We offer strategies that may be used to address anti‐LGBTQ+ sex education laws by school administrators and practitioners in a call for advocacy to make changes in sex education policy to improve the well‐being of students, particularly LGBTQ+ youth. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Seul Ki Choi; José Bauermeister; Ryan C. Tingler; Sherri Johnson; Nicole Macagna; Ken Ho; Craig Hoesley; Albert Liu; Noel Kayange; Thesla Palanee-Phillips; Suwat Chariyalertsak; Pedro Gonzales; Jeanna M. Piper; ; Abigail Mnemba; Alinafe Kamanga; Annie Munthali; Daniel Gondwe; Linly Seyama; Yamikani Mbilizi; Mary Chadza; Josiah Mayani; Helen Rees; Kerushini Moodley; Krishnaveni Reddy; Andile Twala; Ashleigh Jacques; Tsitsi Nyamuzihwa; Nazneen Cassim; Ana Miranda; Diana Morales; Helen Chapa; Javier Valencia; Milagros Sabaduche; Karina Pareja; Katherine Milagros; Charri Macassi; Pongpun Saokhieo; Veruree Manoyos; Nataporn Kosachunhanan; Piyathida Sroysuwan; Allison Matthews; Amy Player; Andrea Thurman; Carol Mitchell; Christine O’Neill; Christy Pappalardo; Christopher Quan; Cindy Jacobson; Clifford Yip; Craig Hoesley; Danielle Camp; Deon Powell; Devika Singh; Diana Ng; Edward Livant; Elizabeth Brown; Emily Helms; Emily Schaeffer; Faye Heard; Gina Brown; Gustavo Doncel; Holly Gundacker; Hyman Scott; Jackie Fitzpatrick; James Gavel; Jenna Weber; Jennifer Schille; Jessica Webster; Jessica Maitz; Jillian Zemanek; Jim Pickett; Jonathan Lucas; Julie Nowak; Kathleen Dietz; Krissa Welch; Kristine Heath; Lisa Rohan; Lizardo Lacanlale; Lynn Mitterer; Lorna Richards; Marcus Bolton; Mei Song; Naana Cleland; Nicholas Ng; Nnennaya Okey-Igwe; Onkar Singh; Patricia Peters; Rebecca Giguere; Renee Weinman; Roberta Black; Scott Fields; Sharon Riddler; Sharon Hillier; Sherri Karas; Stacey Edick; Sufia Dadabhai; Susan Buchbinder; Taha Taha; Tarana Billups; Teri Senn; Theresa Wagner; Tim McCormick; Yuqing Jiao
In: BMC Public Health, vol. 23, no. 1, 2023, ISSN: 1471-2458.
@article{Choi2023c,
title = {A latent trajectory analysis of young sexual and gender minorities’ adherence to three rectal microbicide placebo formulations (MTN-035; a randomized crossover trial)},
author = {Seul Ki Choi and José Bauermeister and Ryan C. Tingler and Sherri Johnson and Nicole Macagna and Ken Ho and Craig Hoesley and Albert Liu and Noel Kayange and Thesla Palanee-Phillips and Suwat Chariyalertsak and Pedro Gonzales and Jeanna M. Piper and and Abigail Mnemba and Alinafe Kamanga and Annie Munthali and Daniel Gondwe and Linly Seyama and Yamikani Mbilizi and Mary Chadza and Josiah Mayani and Helen Rees and Kerushini Moodley and Krishnaveni Reddy and Andile Twala and Ashleigh Jacques and Tsitsi Nyamuzihwa and Nazneen Cassim and Ana Miranda and Diana Morales and Helen Chapa and Javier Valencia and Milagros Sabaduche and Karina Pareja and Katherine Milagros and Charri Macassi and Pongpun Saokhieo and Veruree Manoyos and Nataporn Kosachunhanan and Piyathida Sroysuwan and Allison Matthews and Amy Player and Andrea Thurman and Carol Mitchell and Christine O’Neill and Christy Pappalardo and Christopher Quan and Cindy Jacobson and Clifford Yip and Craig Hoesley and Danielle Camp and Deon Powell and Devika Singh and Diana Ng and Edward Livant and Elizabeth Brown and Emily Helms and Emily Schaeffer and Faye Heard and Gina Brown and Gustavo Doncel and Holly Gundacker and Hyman Scott and Jackie Fitzpatrick and James Gavel and Jenna Weber and Jennifer Schille and Jessica Webster and Jessica Maitz and Jillian Zemanek and Jim Pickett and Jonathan Lucas and Julie Nowak and Kathleen Dietz and Krissa Welch and Kristine Heath and Lisa Rohan and Lizardo Lacanlale and Lynn Mitterer and Lorna Richards and Marcus Bolton and Mei Song and Naana Cleland and Nicholas Ng and Nnennaya Okey-Igwe and Onkar Singh and Patricia Peters and Rebecca Giguere and Renee Weinman and Roberta Black and Scott Fields and Sharon Riddler and Sharon Hillier and Sherri Karas and Stacey Edick and Sufia Dadabhai and Susan Buchbinder and Taha Taha and Tarana Billups and Teri Senn and Theresa Wagner and Tim McCormick and Yuqing Jiao},
doi = {10.1186/s12889-023-17368-y},
issn = {1471-2458},
year = {2023},
date = {2023-12-00},
journal = {BMC Public Health},
volume = {23},
number = {1},
publisher = {Springer Science and Business Media LLC},
abstract = {Abstract
Background
Rectal microbicides (RM) are biomedical HIV prevention products that aim to prevent or reduce the transmission of HIV and other sexually transmitted infections (STIs). RM modalities may be beneficial for populations who have complex lifestyles, difficulties adhering to pre-exposure prophylaxis (PrEP) regimens, and/or have limited access to care. MTN-035 (DESIRE; Developing and Evaluating Short-Acting Innovations for Rectal Use), a randomized crossover trial, aimed to evaluate the safety and acceptability of, and adherence to, three placebo RM modalities (douche, insert, and suppository) prior to receptive anal intercourse.
Methods
We conducted latent trajectory analysis to identify clusters of individuals who shared similar trajectories in acceptability and adherence for each product (douche, insert, and suppository) over time. We analyzed weekly short messaging service (SMS) use reports for each modality as reported by enrolled sexual and gender minority (SGM) participants.
Results
Two trajectories for each product were identified: a “protocol compliant” trajectory (i.e., at least one product use occasion per week) and “high use” trajectory (i.e., more than three product use occasions per week). Participants with high use were more likely to lack access to PrEP and have higher intentions to utilize RM modalities compared to those who were protocol compliant.
Conclusions
This study highlighted high adherence to RM modalities among SGM. As research into viable HIV prevention modalities continues to evolve, tailored intervention strategies are needed to support the uptake of and adherence to alternative prevention modalities that are behaviorally congruent with targeted users.
Trial registration
NCT03671239 (14/09/2018).
},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Seul Ki Choi; Emma Bruehlman-Senecal; Amy Green; Josh Lavra; José Bauermeister
Patterns of engagement in digital mental health intervention for LGBTQ+ youth: a latent profile analysis Journal Article
In: Front. Digit. Health, vol. 5, 2023, ISSN: 2673-253X.
@article{Choi2023b,
title = {Patterns of engagement in digital mental health intervention for LGBTQ+ youth: a latent profile analysis},
author = {Seul Ki Choi and Emma Bruehlman-Senecal and Amy Green and Josh Lavra and José Bauermeister},
doi = {10.3389/fdgth.2023.1254929},
issn = {2673-253X},
year = {2023},
date = {2023-11-23},
journal = {Front. Digit. Health},
volume = {5},
publisher = {Frontiers Media SA},
abstract = {Engagement is a key metric that researchers can use to assess whether participants received the intended dose of a digital health intervention. However, the prevailing approach has predominantly focused on individual paradata metrics, resulting in a fragmented understanding of overall engagement. To address this limitation, our study utilizes person-centered approaches that allow for the simultaneous capture of multiple engagement metrics within imi– a web application specifically designed to support the mental health of lesbian, gay, bisexual, transgender, queer, and other sexual and gender minority youth (LGBTQ+ youth). This person-centered approach enabled us to explore the association between engagement patterns and stress appraisal outcomes within the imi intervention arm. Utilizing latent profile analysis, we classified users into two engagement forms: overall engagement (total number of sessions, pages visited, and external links clicked and their cumulative time spent using imi ) and content engagement (number of pages viewed across imi 's four core guides: gender, stress, queerness, and stigma). We identified two profiles for each form: a “high engagement” profile and an “average engagement” profile, with the majority of participants assigned to the “average engagement” profile. Our analyses revealed a significant association between overall engagement profiles and stress appraisals, with the “high engagement” profile demonstrating higher challenge appraisals and marginal improvements in threat appraisals compared to the “average engagement” profile. However, no such associations were observed for content engagement profiles and stress appraisal outcomes. The two person-centered approaches used were consistent with prior results utilizing a variable-centered approach, indicating a stronger intervention effect among individuals who exhibit higher engagement in digital health interventions. Although both methods yielded comparable findings, the person-centered approach mitigates concerns related to multi-collinearity and adds additional nuance and context to the study of digital engagement. },
keywords = {},
pubstate = {published},
tppubtype = {article}
}